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Oxidants in Biology

by Giuseppe Valacchi
Publisher: Springer Science & Business Media
Release Date: 2008-06-06
Genre: Medical
Pages: 176 pages
ISBN 13: 0877882487
ISBN 10: 9780877882480
Format: PDF, ePUB, MOBI, Audiobooks, Kindle

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Synopsis : Oxidants in Biology written by Giuseppe Valacchi, published by Springer Science & Business Media which was released on 2008-06-06. Download Oxidants in Biology Books now! Available in PDF, EPUB, Mobi Format. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. -- Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.

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Oxidants in Biology
Language: en
Pages: 328
Authors: Giuseppe Valacchi, Paul A. Davis
Categories: Medical
Type: BOOK - Published: 2008-06-06 - Publisher: Springer Science & Business Media

Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
Oxidants and Antioxidants
Language: en
Pages: 356
Authors: Donald Armstrong
Categories: Medical
Type: BOOK - Published: 2002 - Publisher: Springer Science & Business Media

It is now feasible to identify subcellular sites where oxidative stress reactions occur and to determine gene expression relevant to those complex pathways. In Oxidants and Antioxidants: Ultrastructure and Molecular Biology Protocols, a panel of world authorities present cutting-edge molecular and ultrastructure techniques for investigating the pathophysiology of oxidative stress. Described in step-by-step detail, these readily reproducible methods use the latest in immunodetection, X-ray diffraction, confocal microscopy, in situ hybridization, chemiluminescence, and cytofluorescence. Additional techniques take advantage of electron paramagnetic resonance, advanced glycation endproducts, Western blotting analysis, transcription factors, p47phox translocation, and microsphere delivery systems. The collection emphasizes the visual observation of free radicals or products altered by oxidative stress, and includes numerous in vivo, ex vivo, and in vitro applications. Two companion volumes, Oxidative Stress Biomarkers and Antioxidant Protocols (2002), and Free Radical and Antioxidant Protocols (1998), focus on the related biochemical and cellular biological methods. Authoritative and highly practical, Oxidants and Antioxidants: Ultrastructure and Molecular Biology Protocols provides a comprehensive collection of powerful ultrastructure and molecular tools for the evaluation of metabolic disorders linked to oxidative stress and the aging process.
Oxidants in Biology
Language: en
Pages: 328
Authors: Giuseppe Valacchi
Categories: Medical
Type: BOOK - Published: 2009-08-29 - Publisher: Springer

Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
Oxidants and Antioxidants in Cutaneous Biology
Language: en
Pages: 193
Authors: Jens Thiele, Peter Elsner
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Type: BOOK - Published: 2001-01-01 - Publisher: Karger Medical and Scientific Publishers

Are free radicals and reactive oxygen species relevant to dermatopathology? Do antioxidants protect against free-radical-mediated cutaneous diseases and aging? To these and further current questions in the rapidly progressing field of basic and applied skin research, this up-to-date volume provides a scientific basis. It presents state-of-the-art reviews on the progress in detection of free radicals and antioxidants and their responses to environmental oxidative stressors. Furthermore, several expert contributions focus on the exciting developments in oxidative DNA damage and UVB- and UVA-induced signal transduction in skin. Finally, information is given on new antioxidant protection strategies against skin carcinogenesis and skin aging which may be fundamental for the pharmaceutical or skin-care products of tomorrow. Due to its unique and up-to-date collection of state-of-the-art contributions by many of the world's leading scientists in the field, this book will be essential reading for dermatologists, cosmetologists, pharmacologists and environmental toxicologists.
Oxidants and Antioxidants in Biology
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Books about Oxidants and Antioxidants in Biology
Measuring Oxidants and Oxidative Stress in Biological Systems
Language: en
Pages: 237
Authors: Lawrence J. Berliner, Narasimham L. Parinandi
Categories: Science
Type: BOOK - Published: 2020-08-08 - Publisher: Springer Nature

This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
Methods in Molecular Biology: Oxidants and antioxidants: ultrastructure and molecular biology protocols
Language: en
Pages:
Authors: John M. Walker
Categories: Molecular biology -- v.236. Plant functional genomics -- v.237. G protein signaling -- v.238. Biopolymer methods in tissue engineering -- v.239. Cell migration in inflammation and immunity -- v.240. Mammalian artificial chromosomes -- v.241. Cell cycle checkpoint control protocols -- v.242. Atomic force microscopy -- v.243. Chiral separations: Methods and protocols -- v.244. Protein purification protocols -- v.245-6. Gene delivery to mammalian cells -- v.247. Drosophila cytogenetics protocols -- v.248. Antibody engineering -- v.249. Cytokine protocols -- v.251. HPLC of peptides and proteins: Methods and protocols -- v.265. RNA interference, editing, and modification -- v.274. Photosynthesis research protocols -- v.318. Plant cell culture protocols -- v.323. Arabidopsis protocols
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Books about Methods in Molecular Biology: Oxidants and antioxidants: ultrastructure and molecular biology protocols
Oxidants and Antioxidants in Biology
Language: en
Pages: 218
Authors: Oxygen Club of California (Estados Unidos). World Congress
Categories: Molecular biology -- v.236. Plant functional genomics -- v.237. G protein signaling -- v.238. Biopolymer methods in tissue engineering -- v.239. Cell migration in inflammation and immunity -- v.240. Mammalian artificial chromosomes -- v.241. Cell cycle checkpoint control protocols -- v.242. Atomic force microscopy -- v.243. Chiral separations: Methods and protocols -- v.244. Protein purification protocols -- v.245-6. Gene delivery to mammalian cells -- v.247. Drosophila cytogenetics protocols -- v.248. Antibody engineering -- v.249. Cytokine protocols -- v.251. HPLC of peptides and proteins: Methods and protocols -- v.265. RNA interference, editing, and modification -- v.274. Photosynthesis research protocols -- v.318. Plant cell culture protocols -- v.323. Arabidopsis protocols
Type: BOOK - Published: 1998 - Publisher:

Books about Oxidants and Antioxidants in Biology
Food Oxidants and Antioxidants
Language: en
Pages: 568
Authors: Grzegorz Bartosz
Categories: Medical
Type: BOOK - Published: 2013-06-21 - Publisher: CRC Press

Food antioxidants are of primary importance for the preservation of food quality during processing and storage. However, the status of food depends on a balance of antioxidants and prooxidants occurring in food. Food Oxidants and Antioxidants: Chemical, Biological, and Functional Properties provides a single-volume reference on the effects of naturally occurring and process-generated prooxidants and antioxidants on various aspects of food quality. The book begins with a general introduction to oxidation in food and then characterizes the main oxidants present in food, including enzymatic oxidants. Chapters cover oxidation potential, mechanisms of oxidation of the main food components (proteins and lipids), addition of exogenous oxidants during food processing, and the effects of physical agents such as irradiation, freeze-thawing, and high hydrostatic pressure during processing. The book also discusses the effects of oxidation on sensory characteristics of food components and analyzes how oxidation and antioxidants affect the nutritive and health-promoting features of food components. The text examines natural antioxidants in food, including lesser-known ones such as amino acids and polysaccharides, antioxidants generated in food as a result of processing, mechanisms of antioxidant activity, and measurement of antioxidant activity of food components. It explores the bioavailability of curcuminoid and carotenoids antioxidants and presents case studies on natural food antioxidants, presenting novel extraction methods for preservation of antioxidant activity. The final chapters address functional antioxidant foods and beverages as well as general ideas on the effects of food on the redox homeostasis of the organism.
Biological Oxidants and Antioxidants
Language: en
Pages: 372
Authors: Lester Packer, Augustine S. H. Ong
Categories: Science
Type: BOOK - Published: 1998 - Publisher: Amer Oil Chemists Society

This book contains the proceedings of the SFRR-Asia/COSTAM/UNESCO-MCBN Workshop on Biological Oxidants and Antioxidants: Molecular Mechanisms and Health Effects. This workshop covered topics of fundamental importance in basic biological research and in the biomedical sciences.
Oxidative Stress and Antioxidant Defenses in Biology
Language: en
Pages: 448
Authors: Sami Ahmad
Categories: Science
Type: BOOK - Published: 2012-02-05 - Publisher: Springer

This pioneering volume provides the first comprehensive treatment of the latest research on oxidative stress and antioxidant defenses in all types of aerobic organisms. Unlike existing books which concentrate on oxidative stress in humans and other mammals, this unique book investigates oxidative stress in prokaryotes, protists, plants, fungi, vertebrates, and invertebrates, stimulating cross-fertilization among diverse fields. In addition, it explains the basic science of oxygen activation and oxidative stress as a foundation for more advanced material, making this book a valuable resource for both specialists and non-specialists. Topics discussed include: * conversion of oxygen into reactive oxygen species (ROS), as well as reactions involving carbon-centered free radicals, antioxidant molecules, and the oxoferryl complex * ROS-mediated pathologies, from microvascular injury to atherosclerosis to cancer * mechanisms and benefits of ROS production in plants, with attention to conditions of nitrogen fixation * effects of manmade prooxidants found in drugs,pesticides, and environmental pollutants such as mercury and dioxins * metabolic resistance to naturally occurring prooxidants, antioxidant enzymes and proteins, and antioxidant molecules found in natural substances, with kinetics and rate constants for various interactions between ROS and antioxidants * complex genetic responses to ROS-mediated stress, using research on E. coli and S. typhimurium. Integrating a wide range of research, this outstanding book gives a broad and in-depth perspective on current progress in our understanding of oxidative stress. Biochemists and biologists in medicine, toxicology, ecology, entomology, plant science, microbiology, and mycology will benefit from this accessible and insightful treatment of the subject.
Biological Oxidants: Generation and Injurious Consequences
Language: en
Pages: 264
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Categories: Health & Fitness
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Biological Oxidants: Generation and Injurious Consequences is a collection of papers that describes research work done concerning molecules of the intracellular and plasma membrane generating system in leukocytes; the intracellular interactions in oxidant-induced cellular injury; malignant transformation; and intracellular mechanism of oxidant formation. One paper reviews biological oxidants and the molecular basis of chronic granulomatous disease, particularly on compositions found within the plasma membrane. One such composition concerns the discovery of a flavocytochrome b as the central electron-transporting molecule in this system. Another paper examines the early injury of cells caused by external oxidants and the consequences of DNA damage. Other papers review the metabolism of vascular endothelial-derived reactive species, the calcium-modulated cellular effects of oxidants, as well as, the mechanism of inflammatory oxidant damage in tissues. This book is suitable for biochemists, microbiologists, and academicians whose works involve research of cell membranes.